• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    A membrane diffusion device such as a membrane oxygenator is disclosed which comprises a stack of flat membrane wall pairs and flat membrane supports in alternating, interleaving relation. The stack is disposed in a casing and includes an inflatable member disposed between the opposite major faces of the stack and the casing. A flow conduit provides communication between the inflatable member and the exterior through the casing, to permit pressurization of the opposite major faces of the stack while simultaneously providing sealing for the same faces.
    公开号:SU805936A3
    申请号:SU752149103
    申请日:1975-06-19
    公开日:1981-02-15
    发明作者:Вольф Людвиг (Младший)；Г.Сивернс Роберт
    申请人:Бакстер Травеная Лабораториз Инк (Фирма)；
    IPC主号:
    专利说明:

    one
    The invention relates to medical technology, in particular to a membrane diffusion device for blood.
    A diffusion device for blood is known, which contains a package of semipermeable membranes and support plates, a housing with channels for supplying and discharging blood and working medium, and an inflatable padding L1.
    Such a diffusion device contains an inflatable pad and a hemodialysis unit housed in a special frame supported on a pad intended for supplying the node with pressure. An air pad may overlap to the required pressure of a pear with a bagged type device. However, this device uses an airbag located near the hemodialysis unit on one side and characterized by compliance, which leads to their contraction along the edges of the device. This reduction results in insufficient pressure build up near the edges of the packaged membrane, as a result of which the efficiency of the device as a whole decreases.
    The purpose of the invention is to increase the mass transfer of blood.
    This goal is achieved by the fact that the inflatable gasket covers the two side planes of the package and the end surface of the package on the side of the channels for supplying the working medium.
    In addition, there is a mesh inside the inflatable pad.
    0
    The body is made in the form of a box with a hermetically closed loop.
    FIG. 1 shows a diffusion device for blood; in fig. 2 section aa in FIG. 1; in fig. 3 5 section bb in fig. 2; in fig. 4, bottom view of the device in FIG. 5 laying before assembly; in FIG. 6, section B-B in FIG. five.
    Diffusion device 1 for cropping; with;.; A package 2 of semipermeable membranes alternating with supporting plates is inserted. The pairs of membranes and support plates can be made from a single membrane band supporting a mesh membrane located on a corrugated substrate to impart tortuosity. Package 2 contains a large number of channels 3 pockets type for blood streams with one
    0 side of the membrane and a large number of interleaved channels 4 for oxygen on the other side of the membrane.
    Package 2 is located in case 5, which is an integral construction made of molded plastic with an open top, flange b passes around the open top of case 5, to which, after installation in package 2 case, cover 7 is sealed. O-shaped sealing ring 8, made from a silicon elastomer that cures at room temperature, provides additional sealing. The cover 7 may also be glued to the flange 6.
    During the assembly process, the bottom surface of the cover 7 is covered with a layer of adhesive substance, such as a silicon elastomer that cures at room temperature, in order to seal the upper edge 9 of the package 2.
    There are also holes in the lid 7.
    10 and 11, closed with sterile sealed covers, used to connect the supply and discharge pipe for blood. Hole 10 and
    11 are made on the crossbars 12 and -13, which, in turn, seal the elongated windows 14 formed in the lid 7, located across the package 2 and serve to provide communication with each of the channels 3 between the membrane pairs, thereby fulfilling the role of inlet and outlet pipeline respectively for blood
    13 channels 3.
    Oxygen window 15 and 16 in the form of slots made on the basis of the housing 5. f
    The cuts 17 and 18 are made in separate adjacent parts of the rigid substrate in order to jointly form directional channels for each flow of the bag, passed through the entire depth of the bag, promoting the efficiency of the flow of both blood and oxygen through the membrane diffusion oxygenation site.
    The outer gasket 19 is designed to selectively pressurize the bag 2 in order to balance the blood pressure through the bag, which tends to expand the bag and cause an undesirable increase in the thickness of the blood channels. The Proc 19 contains two plastic elista 20 and 21, which are sealed each other along the edges 22 using thermo-compacted or otherwise. The tube 23 communicates with the internal cavity of the inflatable pad 19 through the sheet 20 by means of a corresponding connecting seal 24 located between the tube 23 and the sheet 19. The tube is a pumping device, as a result of which the pad is in the assembled state in a diffusion
    device, the tube 23 passes through a hole made in the base of the housing 5, with the result that the gasket 19 can be pumped outside the diffusion device. Inflatable pad 19 also contains a weave 25, made of woven fiberglass strip covered with venyl, located between sheets 19 and 20 and used to more evenly distribute the gas of the inflatable pad 19 of the element.
    When installed in a diffusion device, the inflatable gasket is folded around the package 2 so as to overlap the opposing main surfaces 26 and 27 of the package 2, as well as the side surface 28 into the base of the package, which is located between the main surfaces 26 and 27. To accomplish this, the gasket bends along two lines 29 and 30 to form three sections, two end sections 31 and 32 and one intermediate section 33, as a result of which the inflatable pad 19 becomes V-shaped in cross section, as shown in FIG. 2. Thus, when the gasket is inflated through the tube 23, all three sections 31, 32 and 33 of it are pumped and ofiH tightly squeezes the bag 2 between them. At the same time, the bag 2 moves upward under the effect of blowing: Section 33 (Fig. 2), as a result, during operation the bag 2 is hermetically pressed against the ring 8 of the cover 7. Consequently, there is less likelihood that the stresses arising during the work destroy the connection between the bag 2 and the seals of the surface 28, which is near most of the channels 3 for flows blood through package 2.
    In addition, the V-shaped inflatable gasket 19 provides for sealing substantially all of the lateral or lower surface 28 of the bag, which significantly reduces or completely eliminates the need for sealing with rubber sealing and is an important advantage in manufacturing.
    Moreover, the bottom surface 28 of the bag 2 is completely sealed, since the surface is completely covered by an inflatable pad 19. Moreover, the phenomenon of shortening the pad 19 is significantly reduced at its outer ends 34, since the two sections 31 and 32 only inflate by half the thickness of the usual one pad. Thus, the waste of the ends 34 from the upper surface 35 of the bag 2 for sections 31 and 32 is significantly reduced, as a result of which most of the upper surface 35 remains sealed. Usually, for convenience of assembly, non-invasive outer ends 33 are made below the 3.2 mm bottom of the upper surface 35 of the package 2, although this distance may be shorter, if necessary, or the ends 33 may even cover the surface 35.
    The housing 5 is made with a small cone directed towards the upper opening, which simplifies the molding process. This can be done without any consequences, since the different thickness of the space resulting from such a taper j is filled with two inflatable sections 30 and 31.
    The long strips of the membrane or supporting plates are corrugated together with the formation of channels 3 and 4, as described above, in order to form a large number of first channels 3 located across the membranes on one side and a large number of second channels 4 running across the membranes on the other. its sides, and in contact with the base plate. The inflatable gasket is located at some distance from the side surfaces 36 and 37 of the package 2 to form flow lines in the area of the recesses 17 and 18, which are adjacent to the ends of the first and second channels for communication with these channels. In this area, the sealing action is inflatable.
    gaskets are not required, since channels for increased depth of blood and oxygen are needed to over-supply the corresponding fluids to the corresponding lines in package 2.
    权利要求:
    Claims (3)
    [1]
    1. A blood diffusion device containing a package of semipermeable membranes and support plates, a housing with channels for supplying and discharging blood and working medium, and an inflatable pad, characterized in that, in order to increase blood mass transfer, the inflatable pad covers two side planes of the pack and end surface of the package from the side of the channels for supplying the working medium.
    [2]
    2. The device according to claim 1, about tl and that the grid is located inside the inflatable pad.
    [3]
    3. The device according to Clause 1, about t l and that the case is made in the form of a box with a hermetically closed lid.
    Sources of information taken into account in the examination
    1. US patent 3526321, cl. 210-321, 1970.
    36
    and
    H
    five
    2S
    thirty
    "
    b-6
    sixteen
    类似技术:
    公开号 | 公开日 | 专利标题
    SU805936A3|1981-02-15|Diffusion device for blood
    US4075091A|1978-02-21|Method for effecting heat or mass transfer
    US3839204A|1974-10-01|Integral blood heat and component exchange device and two flow path membrane blood gas exchanger
    JP4514246B2|2010-07-28|Method for hermetic joining of two membranes
    US5109560A|1992-05-05|Ventilated air mattress with alternately inflatable air cells having communicating upper and lower air chambers
    US3612281A|1971-10-12|Parallel membranous layer type fluid diffusion cell
    US6302988B1|2001-10-16|Air mattress and method of making same
    US4219422A|1980-08-26|Apparatus for mass transfer between fluids, provided with an interposed selectively permeable diaphragm unit
    US3266629A|1966-08-16|Gas and liquid exchange apparatus
    EP0036926B1|1984-08-22|A device for the diffusion of substances between two fluids via semipermeable membranes
    US4318813A|1982-03-09|Membrane plasmapheresis module
    US4165287A|1979-08-21|Potting pleated membrane
    US4411872A|1983-10-25|Water unit for use with a membrane blood oxygenator
    US4239625A|1980-12-16|Potting pleated membrane
    US3526321A|1970-09-01|Disposable artificial kidney
    US4204963A|1980-05-27|Sealing members for a membrane diffusion device
    US4231879A|1980-11-04|Apparatus for selective separation of matter through semi-permeable membranes
    US4411784A|1983-10-25|Stacked plate transfer device
    SE461632B|1990-03-12|MEMBRANE TYPE BLOOD OXYGENATOR
    US2124861A|1938-07-26|Dialytic apparatus
    US3729098A|1973-04-24|Treating blood
    US4199458A|1980-04-22|Membrane diffusion device with external compression
    US4308230A|1981-12-29|Blood oxygenator
    RU1790985C|1993-01-30|Membrane apparatus
    FR2346616A1|1977-10-28|Dialysis chambers constructed with aid of inflatable rubber inserts - to prevent inlet-outlet blockage during sealant injection
    同族专利:
    公开号 | 公开日
    AU8231475A|1976-12-23|
    SE7507130L|1975-12-21|
    ZA753877B|1976-05-26|
    FR2275235B1|1981-09-18|
    ES438758A1|1977-03-16|
    NL7507354A|1975-12-23|
    SE419501B|1981-08-10|
    DE2527255C3|1979-03-15|
    DE2527255A1|1976-01-08|
    DE2527255B2|1978-07-20|
    AR205385A1|1976-04-30|
    US3879293A|1975-04-22|
    CH598849A5|1978-05-12|
    FR2275235A1|1976-01-16|
    BR7503888A|1976-07-06|
    IL47492D0|1975-08-31|
    IL47492A|1978-12-17|
    BE830421A|1975-10-16|
    CA1052285A|1979-04-10|
    IT1039141B|1979-12-10|
    GB1489522A|1977-10-19|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    GB1203582A|1966-10-10|1970-08-26|Nat Res Dev|Improvements in or relating to dialysers|
    FR1597874A|1968-12-16|1970-06-29|
    US3585131A|1969-04-24|1971-06-15|Becton Dickinson Co|Pleated memberane exchange device|
    US3723305A|1971-01-13|1973-03-27|Vital Assists|Hemodialysis|
    BE790299A|1972-03-10|1973-02-15|Atomic Energy Commission|FOLDED DIAPHRAGM DIALYZER, AND PROCESS FOR FORMING IT|JPS5544619B2|1974-12-23|1980-11-13|
    US4028252A|1975-06-04|1977-06-07|Extracorporeal Medical Specialties Inc.|Accordion fold flat plate dialyzer|
    US3992302A|1975-08-28|1976-11-16|Extracorporeal Medical Specialities Inc.|Dialyzer baffle|
    GB1562765A|1976-04-02|1980-03-19|Medical Inc|Semi-permeablemembrane apparatus|
    DE2754220C2|1977-12-06|1982-10-28|SECON Gesellschaft für Separations- und Concentrationstechnik mbH, 3400 Göttingen|Dialyzer|
    AU526360B2|1978-01-23|1983-01-06|Baxter Travenol Laboratories Inc.|Membrane diffusion system|
    DE2803344C3|1978-01-26|1981-09-24|Sartorius GmbH, 3400 Göttingen|Device for mass transfer between fluids with the interposition of a membrane|
    US4204963A|1978-07-20|1980-05-27|Baxter Travenol Laboratories, Inc.|Sealing members for a membrane diffusion device|
    US4199458A|1978-08-28|1980-04-22|Baxter Travenol Laboratories, Inc.|Membrane diffusion device with external compression|
    US4256617A|1979-11-01|1981-03-17|Nl Industries, Inc.|Catalyzed non-toxic polyurethane forming compositions and separatory devices employing the same|
    FR2482055B1|1980-05-08|1985-10-04|Sodip Sa|ENVELOPE-FORMING DEVICE FOR A STACK, APPARATUS COMPRISING SAID DEVICE AND METHOD FOR MOUNTING SUCH AN APPARATUS|
    US4556489A|1983-03-09|1985-12-03|Shiley Incorporated|Membrane oxygenator|
    US5514335A|1993-10-25|1996-05-07|Minnesota Mining And Manufacturing Company|Blood oxygenation system and reservoir and method of manufacture|
    US5762868A|1995-11-30|1998-06-09|Minnesota Mining And Manufacturing Company|Blood oxygenator and heat exchanger|
    US6113782A|1998-07-28|2000-09-05|Terumo Cardiovascular Systems Corporation|Potting of tubular bundles in housing|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    US481081A|US3879293A|1974-06-20|1974-06-20|Membrane diffusion device having inflatable member for pressurization and sealing|
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